Program 26.06.2009 Posters of the day with abstracts
Posters of 26.06. with abstracts
To download a single poster-abstract please click on download after each title.
To download all poster-abstracts please click here.
1. Capsule Endoscopy for the Small Bowel in Juvenile Polyposis Syndrome (download)
O. Will, A.J. Postgate, C.H. Frase, A. Fitzpatrick, R.K.S. Phillips, S.K. Clark, St Mark's Hospital, Middlesex, UK
2. Location in the large bowel influences the APC mutations observed in FAP adenomas (download)
O. Will, S.J. Leedham, G. Elia, R.K.S. Phillips, S.K. Clark, I.P.M. Tomlinson, St Mark's Hospital, Middlesex, UK
3. Mutation analysis of the APC gene in Taiwanese FAP families; low incidence of APC germline mutation in FAP families with mixed type of polyps (download)
Jy-Ming Chiang, PS Hsieuh, CR Chang-chen, Chang Gung Memorial Hospital Tao-Yuan, Taiwan
4. MUCOSECTOMY AND STAPLED POUCH-ANAL ANASTOMOSIS (download)
Steffen Bülow, The Danish Polyposis Register, Copenhagen, Denmark
5. IS THE 'MUTATED IN COLORECTAL CANCER' GENE IMPORTANT IN COLON CANCER AFTER ALL? (download)
Pangon L, Sigglekow N, Musgrove EA, Kohonen-Corish M, Garvan Institute of Medical Research, Sydney, Australia
6. A 111kb COPY NUMBER VARIABLE REGION REGULATES THE EXPRESSION OF A NOVEL PHOSPHATASE IN FAMILIAL ADENOMATOUS POLYPOSIS VARIANT PATIENTS (download)
Thean Lai Fun, Loi C, Ho KS, Koh PK, Eu KW & Cheah PY, Singapore General Hospital, Singapore
7. Ethnic variation of MUTYH gene mutations in an Israeli Population Sample (download)
Guy Rosner M.D.1,2, Sharon Simchoni M.Sc2, Avi Orr-Urtreger M.D. PhD2, Ruth Shomrat PhD2, Dani Bercovich PhD3 Hana Strul M.D.1, Revital Kariv M.D.1, Zamir Halpern M.D.1, Paul Rozen MB BS1. 1Dept. of Gastroenterology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel 2Dep. Of Genetics, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel 3Human Molecular Genetics & Pharmacogenetics, Migal - Galilee Bio-Technology Center
8. DEVELOPING A PROTOCOL FOR GENETIC EVALUATION OF APC-NEGATIVE PATIENTS WITH MULTIPLE COLORECTAL ADENOMAS (download)
Guy Rosner M.D.1, Dani Bercovich PhD2, Hana Strul M.D1., Revital Kariv M.D.1, Zamir Halpern M.D.1, Paul Rozen MB BS1. 1Dept. of Gastroenterology, Tel Aviv Medical Center, Tel Aviv, Israel 2Human Molecular Genetics & Pharmacogenetics, Migal - Galilee Bio-Technology Center
9. THE ROLE OF THE NURSE SPECIALIST IN POLYPOSIS AT ST MARK'S HOSPITAL (download)
Jo Rawlings, Kay Neale, The Polyposis Registry, St, Mark's Hospital, London, UK
10. THE LITHUANIAN POLYPOSIS REGISTER: PROGRESS DURING PAST 14 YEARS. (download)
Samalavicius NE, Poskus T. Oncology Institute of Vilnius University and Vilnius Unversity Santariskiu Clinic Center Branch, Vilnius, Lithuania
11. FAMILIAL COLORECTAL CANCER- A PEDIGREE BASED STUDY (download)
Anna Forsberg, Annika Lindblom
Karolinska Institute, Stockholm, Sweden
12. MUTYH VARIANTS IN AUSTRIAN PATIENTS WITH FAMILIAL ADENOMATOUS POLYPOSIS-LIKE SYMPTOMS - A FIRST REPORT (download)
Brigitte Wolf, Silke Gruber, Judith Karner-Hanusch
Medical University of Vienna, Department of Surgery, Research Laboratories, Wien, Austria
13. PREVENTATIVE MANAGEMENT OF DESMOID DISEASE IN FAP (download)
Emma Barrow, Doug Speake, Fiona Lalloo, D Gareth Evans, Jim Hill
Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK
14. Genetic profiles allow distinction of hereditary ovarian cancer (download)
Katarina Domanska, Susanne Malander, Johan Staaf, Anna Karlsson, Åke Borg, Göran Jönsson, Mef Nilbert
Clinical Sciences, Lund, Sweden
15. Bowel phenomena and symptom experience after six months of total colectomy with familial adenomatous polyposis (download)
Yoshie Murakami
dult Nursing, Graduate School of Human Health Sciences, Tokyo Metropolitan University, Tokyo, Japan
16. YOUR INSIGHT MEMBERSHIP (download)
Kay Neale, Tina Isherwood, The Polyposis Registry, St Mark's Hospital, Harrow, Middlesex, UK
17. Replication study supports published CRC susceptibility loci (download)
Susanna von Holst, Simone Picelli, Petra Wessendorf, Kristan Wennmalm, Annika Lindblom
Karolinska Institute, Stockholm, Sweden
18. STUDY OF THE INCIDENCE OF LOW-RISK COLORECTAL CANCER VARIANTS IN THE SWEDISH POPULATION (download)
Picelli S, von Holst S, Wessendorf P, Wennmalm K, Lindblom A
Karolinska Institutet, Department of Molecular Medicine and Surgery, Stockholm, Sweden
19. INDIVIDUALS WITH SUSPECTED HEREDITARY COLORECTAL CANCER AND COLONOSCOPY: ROLE OF HEALTH BELIEF MODEL E CANCER WORRY (download)
Benedito Mauro Rossi, Erika Maria Monteiro Santos, Maria Teresa Cruz Lourenço
Hospital A.C. Camargo, Sao Paulo, Brazil
20. THE MUTATIONAL SPECTRUM OF APC IN GREEK FAP PATIENTS INCLUDING A DISTINCT MUTATION ON THE ALTERNATIVE SPLICE SITE OF EXON 9 (download)
Florentia Fostira1, Georgia Thodi1, George Fountzilas2, 3, Drakoulis Yannoukakos1
1Molecular Diagnostics Laboratory, I/R-RP, National Center for Scientific Research "Demokritos", Athens, Greece
2Department of Medical Oncology, Aristotle University of Thessaloniki,
Papageorgiou Hospital, Thessaloniki, Greece
3Hellenic Cooperative Oncology Group, Athens, Greece
21. VARIABLE GENE EXPRESSION AND REDUCED PENETRANCE IN FAMILIAL ADENOMATOUS POLYPOSIS. (download)
Rohlin A 1, Wernersson J 1, Fritzell K 2, Björk J 2, and Nordling M 1
1) Dept of Clinical Genetics, Sahlgrenska University Hospital, Gothenburg, 2) The Swedish Polyposis Registry, Department of Gastroenterology and Hepatology, Karolinska University Hospital, Solna.
22. Peutz-Jeghers Syndrome: screening and follow-up (download)
Shirley V Hodgson, Andrew D Beggs
St Georges, University of London, London, UK
23. COMPLETION PROCTECTOMY - THREE CASE STUDIES IN FAP PATIENTS WITH ILEO-RECTAL ANASTOMOSIS. (download)
R Man, K Neale, SK Clark.
St. Mark's Hospital, Harrow, Middlesex, UK
24. HISTOPATHOLOGICAL AND GENETICAL ASPECTS OF COLORECTAL CARCINOMA (download)
Sam Ghazi, Nikos Papadogiannakis, Annika Lindblom, Ulrik Lindforss
Dept. of Pathology, Karolinska Institute at Huddinge, Stockholm, Sweden
25. "PEYER'S PATCH" - TWO CASES IN FAMILIAL ADENOMATOUS POLYPOSIS PATIENTS AFTER COLECTOMY. (download)
R Man, St. Mark's Hospital, Harrow, Middlesex, UK
26. Identification of the first pathogenic OGG1 mutation in combination with a MUTYH missense mutation in a colorectal cancer patient (download)
Monika Morak1,2, Trisari Maßdorf1, Martina Kerscher1, Andreas Laner2, Elke Holinksi-Feder1,2 and the German HNPCC Consortium
University Hospital of the Ludwig-Maximilians-University, Campus Innenstadt and MGZ - Center of Medical Genetics, Munich, Germany
27. HOW A NURSE PRACTITIONER SPECIALISING IN POLYPOSIS SUPPORTS BOTH PATIENTS AND DOCTORS (download)
Muditha Samarasinghe, Kay Neale, Pam Nye
The Polyposis Registry,St Marks Hospital, Harrow, Middlesex, UK
28. CHANGING TRENDS IN CAUSES OF MORTALITY FOR PATIENTS WITH FAMILIAL ADENOMATOUS POLYPOSIS (download)
Ashish Sinha, S Rashis, RKS Phillips, SK Clark
St Mark's Hospital, Polyposis Registry, St Mark's Hospital, Harrow, London, UK
29. PTEN Mutation Positive Cowden Syndrome Associated with Duodenal Neoplasia and Colorectal Cancer: Universal Component Neoplasias or Population-Modified Phenotype? (download)
Zohar Levi, Charis Eng, MD, PhD, FACP, Paul Rosen, Inbal Barnes Keidar, Miri Roth, Yaron Niv
Rabin Medical Center, Pethach Tikva, Israel
30. FREEZE-DRIED BLACK RASPBERRIES CAUSE REGRESSION OF RECTAL POLYPS IN FAP (download)
Carol A. Burke MD, Henrietta Hasson RN, Christine Sardo MPH, Li-Shu Wang PhD, Dennis Pearl
PhD, Anthony Buchta RPh and Gary Stoner PhD
Department of Gastroenterology and Hepatology at the Cleveland Clinic, and The Ohio State
University and Central Ohio Compounding Pharmacy, Columbus, Ohio, USA
31. ASSOCIATION BETWEEN COLORECTAL CANCER AND MYH MUTATIONS IN SPORADIC TUMORS AND IN ATTENUATED FAMILIAL POLYPOSIS COLI (AFAP) (download)
Urso E 1, Agostini M 1, Pucciarelli S 1, Mammi I 1, Viel A 2 , Maretto I1, Nitti D 1
1: Clinica Chirurgica 2^, Dipartimento di Scienze Oncologiche e Chirurgiche, Azienda Ospedaliera-Università di Padova, Italy.
2 : Oncologia Sperimentale 1^, Centro Regionale Oncologico -IRCCS, Aviano, Italy
32. Genetic Referrals from Gynaecology Oncology Multidisciplinary Teams - review and outcomes (download)
Jessica Koehler
Prince of Wales Hospital, Randwick, NSW, Australia
33. Allel-specific expression of the APC gene in mutation-negative patients with adenomatous polyposis (download)
Stefanie Vogt, Astrid Kaufmann, Dietlinde Stienen, Nils Rahner, Verena Steinke, Markus M. Nöthen, Per Hoffmann, Stefan Aretz
Institute of Human Genetics, Bonn, Germany
34. Endoscopic treatment of duodenal polyposis in familial adenomatous polyposis (download)
K.S. Boparai, E.M.H. Mathus-Vliegen, J.W. Poley, F.M. Nagengast, S. van Eeden, P. Fockens, E. Dekker
Academic Medical Centre, Amserdam, The Netherlands
35. Difference in characteristics of APC mutations between colonic and extracolonic tumors of FAP patients (download)
Tatsuro Yamaguchi, Takeru Iijima, Keiichi Takahashi, Hiroshi Matsumoto, Michiko Miyaki
Tokyo Metropolitan Komagome Hospital, Tokyo, Japan
36. ARE THERE AGE AND SEX EFFECTS ON THE INFLUENCE OF MUTYH VARIANTS ON COLORECTAL CANCER RISK? (download)
S.M. Farrington, E.Theodoratou, H.Campbell, A.Tenesa, MG Dunlop and the MUTYH meta-analysis Collaboration
University of Edinburgh, Colon Cancer Genetics Group, 4th Floor MRC Human Genetics Unit, Edinburgh, Scotland
37. The use of narrow band imaging with zoom magnification for the endoscopic diagnosis of high risk duodenal adenomas in patients with familial adenomatous polyposis syndrome (download)
K.S. Boparai, F.J.C. van den Broek, S. van Eeden, P. Fockens, E.M. Mathus-Vliegen, E. Dekker
Academic Medical Centre, Amsterdam, The Netherlands
38. c.891+3A>C IS AN ITALIAN RECURRENT MutYH MUTATION ASSOCIATED WITH PRODUCTION OF ABERRANT mRNA TRANSCRIPTS (download)
Viel Alessandra, Pin Elisa, Pastrello Chiara, Fornasarig Mara, Urso Emanuele, Tricarico Rossella, Tibiletti Maria Grazia, Genuardi Maurizio, Quaia Michele
Centro di Riferimento Oncologico, Aviano, Italy
39. P53-regulated Mir-17-92 modulate Hif1A expression under hypoxia (download)
Hong-Li Yan, Geng Xue, Qian Mei, Yuzhao Wang, Shu-Han Sun*
40. MUTYH-associated polyposis carcinomas frequently lose HLA class I expression - a common event amongst DNA-repair deficient colorectal cancers (download)
Noel F.C.C. de Miranda1, Maartje Nielsen2, Dina Pereira1, Marjo van Puijenbroek1, Hans F. Vasen3, Frederik J. Hes2, Tom van Wezel1, Hans Morreau1
1 Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
2 Department of Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands
3 Department of Gastroenterology, Leiden University Medical Center, Leiden, The Netherlands
41. ADENOMATOUS POLYPOSIS COLI GERMLINE MOSAICISM IN A PATIENT WITH CLASSICAL (download)
Judith Necker, Michèle Attenhofer, Bruno Reichlin, Karl Heinimann
Research Group Human Genetics, Department of Biomedicine, Basel, Switzerland
42. Is Familial Adenomatous Polyposis a ciliopathy? (download)
Encarna B. Gomez Garcia, MD,PhD, Nine V.A.M. Knoers, MD/PhD
Dept. of Genetics and Cell Biology, Maastricht, The Netherlands
43. APC GERMLINE ALLELE-SPECIFIC EXPRESSION IN FAMILIAL ADENOMATOUS POLYPOSIS (download)
E. Castellsagué(1), S. González(1), I. Blanco(2), E. Guinó(3), C. Lázaro(1), S. Gruber(4), G. Capella(1)
(1)Laboratori de Recerca Translacional, Institut Català d'Oncologia, IDIBELL, Hospitalet de Llobregat, Spain; (2)Unitat de Consell Genètic, Institut Català d'Oncologia, IDIBELL, Hospital Duran i Reynals, Hospitalet de Llobregat, Spain; (3)Unitat de Bioestadística i Bioinformàtica, Institut Català d'Oncologia, IDIBELL, Hospitalet de Llobregat, Spain; (4)University of Michigan, Ann Arbor, MI, United States
44. HIGH RISK" CLINIC FOR HEREDITARY COLORECTAL NEOPLASIA: A FOCUS FOR PATIENT CARE AND AN OPPORTUNITY FOR CLINICAL RESEARCH (download)
Lisa LaGuardia, Margaret O'Malley BS, Jon D. Vogel MD, Brandie Leach MS CGC, Carol Burke MD Matthew Kalady MD, James Church MBChB
45. HAPLOTYPE ANALYSIS AND AGE ESTIMATION OF THE Y165C AND G382D MUTATIONS IN GERMAN MAP PATIENTS (download)
Stefan Aretz, Stefanie Vogt, Daniela Tavian, Astrid Kaufmann, Dietlinde Stienen, Markus M. Noethen, Sven Cichon, Waltraut Friedl, and Roberto Colombo
Institute of Human Genetics, Bonn, Germany
46. APC ALTERNATIVE SPLICING AS RESPONSIBLE FOR PHENOTYPIC VARIABILITY IN FAMILIAL ADENOMATOUS POLYPOSIS (download)
S. González1, M. Menéndez1, I. Blanco2, A. Obrador-Hevia3, C. Lázaro1, G. Capellá1.
1Translational Research Laboratory, Catalan Institute of Oncology, 2Genetic Counselling Unit, Catalan Institute of Oncology, 3Biology of Cancer Group, University of Balearic Island
47. MYH GENE MUTATION IN CHILEAN PATIENTS WITH COLONIC POLYPOSIS SYNDROMES (download)
1 Francisco López-Köstner, 1K. Alvarez, 1M. De la Fuente, 1E. Pinto, 1U. Kronberg, 1C. Heine, 1A.M. Wielandt, 1,2P. Orellana, 2P. Carvallo.
1Laboratory of Genetics and Molecular Oncology, Colorectal Surgery Unit. Clinica Las Condes. 2Laboratory of Human Molecular Genetics, Catholic University of Chile. Santiago, Chile.
48. COMPUTED TOMOGRAPHIC COLONOGRAPHY TO ASSESS PEROPERATIVE COLORECTAL POLYP BURDEN IN FAMILIAL ADENOMATOUS POLYPOSIS (download)
Margaret O'Malley, James Church M.D, Lisa LaGuardia RN, BSN, Jon D. Vogel M.D., Grace Cheah, RN, MSN, Mark Baker M.D., Carol A. Burke M.D.
Digestive Disease Institute, Sanford R. Weiss, MD Center for Hereditary Colorectal Neoplasia, Cleveland Clinic, Department of Colorectal Surgery, Department of Radiology, Department of Gastroenterology, Cleveland, Ohio, USA
49. LAPAROSCOPIC SURGERY IN PATIENTS WITH COLONIC POLYPOSIS SYNDROMES. (download)
Francisco López-Köstner, C. Heine T., P. Medina T., U. Kronberg, C. Wainstein G. Colorectal Surgery Unit, Clínica las Condes. Santiago, Chile.
50. THE MUTYH GENE VARIANT DATABASE (download)
Astrid A. Out1, Carli M.J. Tops1, Maartje Nielsen1, Marjan M. Weiss1, Hans F.A. Vasen2,3, Johan T. den Dunnen1, Stefan Aretz4, Julian R. Sampson5, Peter Devilee1, Frederik J. Hes1
1Center for Human and Clinical Genetics, 2Department of Gastroenterology, Leiden University Medical Center, 3the Netherlands Foundation for the Detection of Hereditary Tumours, Leiden, The Netherlands, 4Institute of Human Genetics, University of Bonn, Bonn, Germany and 5Institute of Medical Genetics, School of Medicine, Cardiff University, Cardiff, Wales, United Kingdom
51. WNT SIGNALING SOMATIC ALTERATIONS IN APC-ASSOCIATED FAP ADENOMAS. (download)
Antònia Obrador-Hevia1, Feung Chin2, Sara González3, Jonathan Rees2, Felip Vilardell3, Joel Greenson4, Víctor Moreno5, Carlos Caldas2, Gabriel Capellá3
1 Cancer Cell Biology and Translational Oncology Group. Institut Universitari d'Investigació en Ciències de la Salut (IUNICS)-Universitat de les Illes Balears. Illes Balears (Spain).
2 Functional Breast Cancer Genomics Laboratory. Cancer Research UK Cambridge Research Institute. Li Ka-Shing Centre. Cambridge (United Kingdom).
3 Translational Research Laboratory. Catalan Institute of Oncology. Barcelona (Spain).
4 Department of Pathology. The University of Michigan Health System. Ann Arbor (USA).
5 Biostatistics and Bioinformatics Unit. Catalan Institute of Oncology. Barcelona (Spain).
52. DETECTING SOMATIC MOSAICISM OF THE APC GENE WITH HIGH RESOLUTION MELTING CURVE ANALYSIS (download)
A.A. Out1, I.J.H.M. van Minderhout1, A.C. Schaap1, R. Louiszoon1, E.C. Bik1, C.M. Tops1, R.H.A.M. Vossen1, N. van der Stoep1, E. Bakker1, H.F.A. Vasen2,4, H. Morreau3, P. Devilee1,3, F.J. Hes1
1Center for Human and Clinical Genetics, 2Department of Gastroenterology, 3Department of Pathology, Leiden University Medical Center, 4the Netherlands Foundation for the Detection of Hereditary Tumours, Leiden, The Netherlands.
53. THE ROLE OF COMMON MUTYH GENE MUTATIONS IN BREAST CANCER APPEARS INSIGNIFICANT (download)
Astrid A. Out1, Ivonne J.H.M. van Minderhout1, Carli M. Tops1, Maartje Nielsen1, Marjan M. Weijs1, Martijn H. Breuning1, Hans F.A. Vasen2,4, Peter Devilee1,3, Frederik J. Hes1
1Center for Human and Clinical Genetics, 2Department of Gastroenterology, 3Department of Pathology, Leiden University Medical Center, 4the Netherlands Foundation for the Detection of Hereditary Tumours, Leiden, The Netherlands.
54. YOUR PATIENT INFORMATION WEBSITE: HOW GOOD IS IT? (download)
Ramawad Soobrah, Anand Patel, Sue Clark
St Mark's Hospital, Harrow, Middlesex, UK
55. A Survey of Hereditary Adenomatous Polyposis in Quebec (download)
George Chong, Jonathan Jarry, Yury Monczak, Nora Wong, Sonya Zaor, Lidia Kasprzak, Laura Palma, Marc Tischkowitz, and William D. Foulkes
SMBD-Jewish General Hospital, Montreal (QC), Canada
56. COGNITIVE FUNCTION IN FAP: ANYONE OUT THERE LISTENING? (download)
Margaret O'Malley, James Church MD, Lisa LaGuardia RN BSN, Richard Naugle PhD., Cynthia Gensur AuD, Jeff Hammel, Carol A. Burke MD
Digestive Disease Institute, Sanford R. Weiss, MD Center for Hereditary Colorectal Neoplasia, Cleveland Clinic, Department of Colorectal Surgery, Department of Psychology, Department of Audiology, Department of Gastroenterology, Cleveland, Ohio, USA
57. AUDIOLOGY IN FAMILIAL ADENOMATOUS POLYPOSIS: DO YOU HEAR WHAT I HEAR? (download)
Margaret O'Malley, James Church MD, Lisa LaGuardia RN BSN, Richard Naugle PhD., Cynthia Gensur AuD, Jeff Hammel, Carol A. Burke MD
Digestive Disease Institute, Sanford R. Weiss, MD Center for Hereditary Colorectal Neoplasia, Cleveland Clinic, Department of Colorectal Surgery, Department of Psychology, Department of Audiology, Department of Gastroenterology, Cleveland, Ohio, USA
58. The Swedish Polyposis Registry. A national registry for patients with Familial Adenomatous Polyposis, Peutz.Jegher and Juvenile Polyposis (download)
Kaisa Fritzell, Jan Björk, Karin Göransson
The Swedish Polyposis Registry, Karolinska University Hospital, Stockholm, Sweden
59. SATISFACTION WITH CARE, PERCEPTION OF ILLNESS, AND HEALTH-RELATED QUALITY (download)
Kaisa Fritzell, Jan Björk, Rolf Hultcrantz, Lena Wettergren
Department of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm, Sweden
60. DESMOID-RELATED URETERIC OBSTRUCTION IN PATIENTS WITH FAMILIAL ADENOMATOUS POLYPOSIS (download)
Myles Joyce, James Church, Emilio Mignanelli
Sanford R. Weiss Center for hereditary Colorectal Neoplasia, Cleveland, Ohio, USA
61. ADRENAL INCIDENTALOMAS IN FAP PATIENTS (download) A. Hansmann, O.C.C. Will, R.K.S.Phillips, F. F. Palazzo, K. Meeran, M. Marshall , S.K.Clark.
The Polyposis Registry, St. Mark's Hospital, Harrow, United Kingdom
Department of Radiology, St. Mark's Hospital, Harrow, United Kingdom
Department of Endocrine Surgery, Hammersmith Hospital, London, United Kingdom
Department of Endocrinology, Hammersmith Hospital, London, United Kingdom
62. INITIAL RESULTS ON POLYPOSIS RESEARCH IN LATVIA (download)
Viktors Borošenko, Arvīds Irmejs, Andris Gardovskis, Andrejs Vanags, Māris Pavārs, Edvīns Miklaševičs, Genādijs Trofimovičs and Janis Gardovskis
Riga Stradins University, Hereditary Cancer Institute, Latvia;
63. GENOMIC PROFILING DIVIDES FAMILIAL COLORECTAL CANCER INTO TWO DISTINCT SUBGROUPS (download)
Christina Therkildsen1, Göran Jönsson2, Anja Nissen1, Anna Karlsson2, Eva Rambech2, Britta Halvarsson3, Inge Bernstein4, Åke Borg2, Mef Nilbert2,3
1Clinical Research Center, Copenhagen University, Hvidovre University Hospital, Copenhagen, Denmark; 2Departments of Oncology and 3Pathology, Institute of Clinical Sciences, Lund University, Lund, Sweden; 4HNPCC register, Department of Gastroenterology, Copenhagen University, Hvidovre University Hospital, Copenhagen, Denmark
64. SURVEILLANCE RECOMMENDATIONS FOR INDIVIDUALS WITH MUTYH-ASSOCIATED POLYPOSIS AND HYPERPLASTIC POLYPS:THE DILEMMA (download)
Parry S, Woodall S, Walsh MD, McKeone D, Buchanan DD, Young JP, Chow E, Macrae F.
New Zealand Familial Gastrointestinal Registry, Auckland City Hospital, Genetic Services,Auckland City Hospital, Grafton, Auckland, New Zealand
65. ESTABLISHMENT OF A NATIONAL FAMILIAL GASTROINTESTINAL CANCER REGISTRY - A PRELUDE TO BOWEL CANCER SCREENING (download)
Parry S, Collett J, Arnold J, Brunton H, Lomas J
New Zealand Familial Gastrointestinal Registry, Auckland City Hospital, Auckland, New Zealand
66. "NO GRIEVING FOR THE RECTUM": QUALITY OF LIFE IS PRESERVED AFTER PROCTECTOMY AND ILEAL POUCH-ANAL ANASTOMOSIS IN FAMILIAL ADENOMATOUS POLYPOSIS (download)
Andre da Luz Moreira, Margaret O'Malley; Carol Burke; James Church
Cleveland Clinic, Cleveland, USA
67. TREATMENT OF DUODENAL TUMORS IN PATIENTS WITH FAMILIAL ADENOMATOUS POLYPOSIS: TO DOWNGRADE THE STAGE OF DUODENAL LESION (download)
Takeo Iwama [1], Hiroshi Makino [1], Kazuki Taniguchi [1], Hitoshi Sugimoto [1], Mitsuru Obata [2], [3] Yasuyuki Kawachi
[1] Kyoundo Hospital, [2] Obata Clinic, [3] Musashino Red Cross Hospital
68. APC OR MUTYH MUTATIONS ACOUNT FOR THE MAJORITY OF CLINICALLY WELL CHARACTERIZED FAMILIES WITH FAMILIAL ADENOMATOUS POLYPOSIS AND ATTENUATED FAMILIAL ADENOMATOUS POLYPOSIS PHENOTYPE AND PATIENTS WITH MORE THAN 30 ADENOMAS (download)
Bruno Filipe1, Célia Baltazar1, Cristina Albuquerque1, Sofia Fragoso1, Pedro Lage2, Inês Vitoriano1, Susana Mão de Ferro2, Isabel Claro2, Paula Rodrigues2, Paulo Fidalgo2, Marília Cravo2, Carlos Nobre Leitão2 (1- Centro de Investigação de Patobiologia Molecular (CIPM), Instituto Português de Oncologia de Lisboa de Francisco Gentil, EPE, Lisbon, Portugal; 2-Department of Gastroenterology, Instituto Português de Oncologia de Lisboa de Francisco Gentil, EPE, Lisbon, Portugal)
69. APC SOMATIC MOSAICISM IN A PATIENT WITH GARDNER SYNDROME CARRYING THE E1573X MUTATION (download)
Bruno Filipe1, Cristina Albuquerque 1, Elsa Bik 2, Pedro Lage 3, Paula Rodrigues 3, Rolf Vossen 2, Carli Tops 2, Carlos Nobre Leitão 3 (1-Centro de Investigação de Patobiologia Molecular (CIPM), Instituto Português de Oncologia de Lisboa de Francisco Gentil, EPE, Lisbon, Portugal; 2-Center of Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands; 3-Department of Gastroenterology, Instituto Português de Oncologia de Lisboa de Francisco Gentil, EPE, Lisbon, Portugal)
70. VIRTUAL PATHOLOGY DATABASE OF HEREDITARY DISORDERS (download)
H Morreau, NF de Miranda, T van Wezel and future contributors
Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
71. A NOVEL MUTATION IN MUTYH - ASSOCIATED POLYPOSIS (MAP) SYNDROME (download)
Florentia Fostira1, Christos Panopoulos2, Anna Efraimidis2, Drakoulis Yannoukakos1
1N.C.S.R "Demokritos", Molecular Diagnostics Laboratory, R-RP Institute, Athens, Greece
2 Oncology Anticancer Hospital ' Agios Sabbas', 2nd Dept Medical Oncology, Athens, Greece
72. PREVALENCE OF ADENOMAS IN FAMILIAL COLORECTAL CANCER (download)
AE van der Meulen - de Jong1, HJ Wolters3, AMC Witte3, J Vecht3, WR ten Hove3, JMJL Salemans3, FM Nagengast3, JH Kleibeuker3, GF Nelis 3, HFA Vasen1,2
1. Dept. of gastroenterology, Leiden University Medical Center, Leiden, Netherlands.
2. The Netherlands Foundation for the Detection of Hereditary Tumours, Leiden, Netherlands.
3. Member Collaborative Group FACTS Study
73. PREVALENCE OF FEATURES OF CHRONIC PANCREATITIS IN A DUTCH COHORT OF INDIVIDUALS AT HIGH-RISK FOR DEVELOPING PANCREATIC CANCER (download)
F. Harinck1, J-W. Poley1, I. Kluijt5, M.G.W. Dijkgraaf6, R. Timmer3, H.J. van Dullemen4, M.J. Bruno1, P. Fockens2
1.Department of Gastroenterology and Hepatology, Erasmus Medical Center Rotterdam
2. Department of Gastroenterology and Hepatology, Academic Medical Center Amsterdam 3. Department of Gastroenterology and Hepatology, St. Antonius Hospital Nieuwegein
4. Department of Gastroenterology and Hepatology, University Medical Center Groningen 5. Department of Clinical Genetics, Netherlands Cancer Institute Amsterdam
6. Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center Amsterdam
74. PROPHYLACTIC TOTAL GASTRECTOMY (PTG) FOR HEREDITARY DIFFUSE GASTRIC CANCER (HDGC) (download)
P.C. Hebbard, MD1; A. MacMillan, MS2, D. Huntsman, MD3, P. Kaurah, MSc3,
F. Carniero, MD4, A. Kwan, MD1, D. Boone, MD1, F. Bursey, MD1, J. Green,
PhD2, B. Fernandez, MSc, MD2, D. Fontaine, MD5, and D.A. Wirtzfeld, MSc,
MD.7
1Department of Surgery, Memorial University, St John's, Newfoundland &
Labrador, Canada; 2Provincial Medical Genetics Program, Health Sciences Centre, St John's, Newfoundland & Labrador, Canada; 3Hereditary Cancer Program, Vancouver, British Columbia, Canada; 4Instituto de Patologia e Imunologia Molecular da Universidade do Porto (IPATIMUP) and Facildade de Medicina, Hospital S. Joao, Porto, Portugal; 5Department of Internal Medicine, Memorial University, St John's, Newfoundland & Labrador, Canada; 6Department of Pathology, Memorial University, St John's, Newfoundland & Labrador, Canada; 7Departments of Surgery and Oncology, University of Manitoba, Winnipeg, Manitoba, Canada
75. PANCREATIC CANCER SCREENING BY MAGNETIC RESONANCE IMAGING AND ABDOMINAL ULTRASOUND (download)
Spring Holter1, Heidi Rothenmund1, Masoom Haider2, Stephanie Wilson2, Kara Semotiuk1, Steven Narod3, Steven Gallinger1
1Dr. Zane Cohen Digestive Diseases Clinical Research Centre, Familial Gastrointestinal Cancer Registry, Toronto, Ontario, Canada; 2Medical Imaging Department, University Health Network; 3The Centre for Research in Women's Health, Women's College Hospital