07:00 CAPP 2 Breakfast Session Chairpersons: John Burn

Plenary session 4: Basic science, epidemiology FAP and MAP

Chairpersons: Julian Sampson, Steve Gallinger

08:00

A new conditional APC mutant mouse model for colorectal cancer (download)

Els Robanus-Maandag

08:10

Changing causes of death in Familial Adenomatous Polyposis: signs of progress but more work to do (download)

Craig Messick

08:20

MUTYH associated polyposis - variable clinical phenotype and report on novel mutations (download)

Elke Holinski-Feder

08:30

Renal cancer as part of the phenotype of MYH-associated polyposis; the evidence gets stronger (download)

Brandie Leach

08:40

Gentotype-phenotype correlation of MUT-Y (MYH) E466X bi-allelic mutation carriers in the Indian population and G382D/Y165C bi-allelic and compound heterozygote Caucasian population (download)

Christina Thirlwell

08:50

Analysis of MUTYH genotypes and colorectal phenotypes in patients with MUTYH associated polyposis (download)

Maartje Nielsen

09:00

Colorectal cancer risk in MUTYH heterozygotes (download)

Julian Sampson

09:10

Extracolonic tumour spectrum and incidence in 276 MAP patients (download)

Stefan Aretz

09:20

General discussion

09:30 – 10:00 hrs Coffee break

10:00

Bussey lecture

Psychosocial Issues in familial cancer predisposition’

Introduction by Allan Spigelman

Bettina Meiser

Plenary session 5: psychological issues, desmoid disease

Chairpersons: Terri Berk, Sue Clark

10:30

Familial Adenomatous Polyposis (FAP): attitudes towards genetic testing in childhood and reproductive decision-making (download)

Kirsten F.L. Douma

10:40

Compliance with endoscopic surveillance advice for Familial Adenomatous Polyposis (FAP): room for improvement (download)

Kirsten F.L. Douma

10:50

MyFAP: an internet-based psychosocial intervention for adelescents and young adults with FAP (download)

Susan K. Peterson

11:00

Children with Familial Adenomatous Polyposis who underwent early colectomy: psychological, quality of life and pouch outcome (download)

Carol Durno

11:10

General discussion

11:20

Development of desmoid tumor in FAP patients undergoing colectomy: IRA vs IPAA (download)

Matthew Kalady

11:30

Desmoids risk and laparoscopic surgery in FAP (download)

Marco Vitellaro

11:40

Abdominal surgery for desmoid disease in FAP (download)

Matthew Kalady

11:50

General discussion

12:00 – 13:00 hrs Lunch break & Posters

13:00 – 13:30 hrs Business meeting

13:30

Jeremy Jass lecture

Deciphering inherited susceptibility to colorectal cancer

Introduction by Anika Lindblom and Joanne Young

Richard Houlston

Plenary session 6: Treatment colorectal and duodenal polyposis

Chairpersons: Miguel Rodriquez-Bigas, Steffen Bulow

14:00

Is there a genotype-phenotype correlation for ileal pouch polyposis in patients with Familial Adenomatous Polyposis? (download)

Alexander C. von Roon

14:10

Non-surgical management in attenuated Familial Adenomatous Polyposis: the potential role of long-term endoscopic surveillance (download)

Patrick Lynch

14:20

Chemoprevention prevents proctectomy and rectal cancer in FAP (download)

Carol A Burke

14:30

Prophylactic pancreaticoduodenectomy for advanced duodenal adenomatosis in Familial Adenomatous Polyposis (download)

James R A Skipworth

14:40

What happens when you remove the duodenum from a patient without a colon? Is bowel function or quality of life impacted? (download)

Yehuda Kariv

14:50

Outcomes based on management for duodenal adenomas: sporadic versus familial desease (download)

Michael D Johnson

15:00

In Familial Adenomatous Polyposis: multiple targeted endoscopic biopsies are accurate in assessing severity of duodenal adenomatosis (download)

Musa Drini

15:10

Endocrine abnormalities in Familial Adenomatous Polyposis patients (download)

Carol A Burke

15:20

General discussion

15:30 – 16:00 hrs Coffee break

16:00

David Jagelman Consultant Conference

Robin Phillips